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CoMet is a metallic photopolymerized coating with conductive properties and highly reflective mirror effect. Its propertis are obtained thanks to one-step photo-induced aggregation of nanoparticles in a polymer layer. No solvent and no free nanoparticles are used. Used as an ink or performance coating on a variety of substrates, such as plastics, tissues, papers, metals, glass etc.
Development of an innovative catalyst which is metal-free with a carbon-based coating. The catalyst is intended to be used in (petro)chemical and gas industries producing toxic hydrogen sulphide. Its depollution uses metal-based catalysts difficult to recycle. The catalyst's specificity is its substrate and its coating in order to resist alterations and increase its regeneration and recycling.
Small molecule (NCE) agonist of sigma1 receptor for the treatment of several neurodegenerative diseases. 2 chemical series, protected by 2 patents, highly selective and affine. Preliminary in-vivo data available on Alzheimer's, ALS (amyotrophic lateral sclerosis) and CIAS (cognitive impairement associated with schizophrenia) models.
Neuropathic pain is thought to affect 6–8% of the general population, with a significant impact on patients’ quality of life. Targeting multiple mechanisms of pain is likely to be the best approach to pain management. The goal of DELIS-NEP project is to develop new molecules with multimodal action (sigma1/NET/SERT) and demonstrate their effectiveness using multiple models of neuropathic pain.
Dermapol is an innovative tool which helps skin pathologies diagnosis, such as melanoma. Detecting a polarimetric signature of pathologic tissues, it brings a considerable and objective help to practitioners. Dermapol device is portable and miniaturised. Currently under clinical study.
This project aims at increasing the therapeutic window of ADCs by developing a linker that releases the payload selectively in cancerous cells.
Using cytometric screening technology, we identified a new linker with unprecedented selectivity for cancer cells which express specific enzymes.
An anti-counterfeiting solution which can be formulated in different matrixes and integrated in marking solutions, such as printing inks. DualEm is a fluorescent molecular structure emitting at 2 specific wavelengths under UV and keeping this capacity at liquid and solid state. The dual emission fingerprint depends on the formulation used, very difficult to counterfeit
Utilization of opioid analgesics is limited by prominent side effects and neuropeptide FF receptors (NPFF1R and 2R) are recognized as important pronociceptive system involved in opioid-induced hyperalgesia and analgesic tolerance. DUALOP project is focused on a development of bifunctional biased mu opioid agonist – NPFFR1/R2 antagonist as analgesics having reduced side effects.
Thanks to the introduction of two different dynamic chemical groups into a polymeric network, this technology brings interesting properties to thermosetting materials, such as better recyclibility, self-healing under heat or solvent action and reversible adhesion to easily detach thermoset materials.
Development of a micro-fabricated plate system that allows for the production of organoids that are reproducible in shape and size
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