Development of new photopolymerisable formulations (under UV or near-infrared LED light) for epoxy-amines resins. These formulations allow a polymerisation within minutes instead of hours, at room temperature without the necessity of thermal cure. Their application is in various fields and markets, such as composites, adhesives etc.

Restoring apelin signaling in sarcopenia considerably enhanced muscles’ function and regenerative capacity. GlucoFAP13 project proposes apelin-13 derivatives stabilized by an innovative technology. Evaluation ongoing for efficacy in improving muscle strength, stamina and endurance in a sarcopenic mouse model.

New antibody fragments for the treatment of thrombosis (stroke, thrombotic purpura, coronary syndrome...). Our approach is directed against a platelet receptor that is not currently targeted by commercially available products, and prevents thrombus formation with a reduced bleeding risk.

A numerical simulation software and plug-in for the training of surgeons including real haptic sensations. The developed method stimulates organs and medical devices for a realistic impression. The latest developments already allowed its application in needle insertion in human tissues and directly in the training of kidney stones removal.

New generation photocatalyst activatable under LED light. The technology is able to perform photopolymerisation of acrylate and epoxy resins thanks to an unique photoredox catalytic cycle at very low copper-based complex concentration. High reactivity and conversion rates, no toxicity. The catalytic complex is also efficient for the polymerisation of dark samples.

Light-Up Nucleic Acid technology based on a light-up RNA aptamer able to specifically recognize a fluorogen and light up a fluorescence signal.
Module with very good properties in term of brightness, photostability and signal to noise ratio. Could overcome current limitations of RNA imaging and could be applied in diagnostic to detect RNA targets with high specificity and sensibility.

Spexin, novel hormone involved in obesity, is markedly downregulated in obese human fat. Repletion of circulating Spexin may help restore normal feeding behaviors and energy balance in obese people. We developed a modified Spexin for the treatment of obesity. Higher efficacy and improved plasma stability compared to native spexin. Next step: in-vivo efficacy study on a DIO-mice model.

Innovation in mirror manufacturing using a photochemical process without solvents, more sustainable, cheaper and with nanometric layer thickness.

Nano 3D is a disruptive technology for 3D high-resolution imaging which increases 4 times the resolution of interferometric microscopes or 3D optical profilometers without increasing their cost.

The project aims to develop a new technology of detection of target molecules (nucleic acid, antigen, toxin etc), based on utilization of polymeric nanoparticles being 1000-fold brighter than individual fluorophore. The detection can be done with simplified inexpensive detection system, e.g. low power excitation sources. A start-up company will be created to develop this technology.